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Ask the Experts about Facial Wasting
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what are the best drugs to prevent facial wasting
Apr 26, 2009

I have been diagnosed about 2 months ago. I am going to start my treatment next month. Do you have any suggestions about what drugs prevent facial wasting and fat loss? Thank you!

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   Response from Dr. Pierone

The medications that are most closely tied to facial thinning and fat loss are d4T (stavudine, Zerit), AZT (zidovudine, Retrovir) and ddI (didanosine, Videx). This is one of the reasons, among others, that these medications are not used as much anymore in the developed world. The most commonly used first line agent, Atripla, is less likely to cause side effects and facial lipoatrophy.

Good luck!



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